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Home / News / The Birth: Our Story & Our Why
autism · fluroide free · mental health · oral health · Our Story · pineal gland · 1 comment · Jan 26, 2025

The Birth: Our Story & Our Why

The Four Pillars That Sparked the Birth of TrnscndWellness

The image above features the Four of Wands, a tarot card symbolizing stability and achievement. For our founder, Nicole Sain, this imagery reflects her personal journey through four pivotal life pillars that ultimately inspired TrnscndWellness:

  • Her mental health journey

  • The discovery of her daughter’s chromosome abnormality

  • A stranger’s unexpected gift to establish TrnscndWellness LLC

  • Awareness of the pineal gland’s connection to fluoride

Mental Health and Her Daughter’s Medical Discovery

Nicole Sain, a proud Chicago native born and raised on the Westside, attended Whitney Young Magnet High School, where she was known for her shy and reserved demeanor. In 2018, Nicole gave birth to twins, and at just six months, she discovered that her twin daughter was born with a rare chromosome abnormality. Later, it was confirmed that her daughter was also on the autism spectrum.

In 2020, Nicole and her husband filed for divorce. Determined not to let life’s challenges overwhelm her—especially with minimal support from her biological family—Nicole began therapy. During her sessions, anti-anxiety medication was recommended, but she decided to explore holistic alternatives instead.

This journey led Nicole to learn about the calming benefits of Sativa. To counteract potential gum issues associated with its use, she incorporated eucalyptus oil and activated charcoal into her oral care routine. While using fluoride-free toothpaste at the time, it wasn’t until she added these ingredients that she experienced a noticeable difference, describing her teeth as having a polished, clean feel.

After months of consistent use, Nicole envisioned creating her own toothpaste. Though she didn’t have a clear path forward, she embraced the challenge, determined to bring her idea to life.

 


 

A Stranger’s Gift to Establish TrnscndWellness

Nicole’s vision for creating a toothpaste brand didn’t come to fruition immediately. In 2021, life threw unexpected hurdles her way, and she began to doubt whether her dream was meant to be. Then, she met someone who would change her trajectory.

While searching for private transportation services for her daughter, Nicole connected with a female business owner. The two shared stories, and Nicole expressed her admiration for the transportation owner’s journey. During their conversation, Nicole mentioned her dream of starting a business.

Without hesitation, the owner offered to gift Nicole the funds to establish TrnscndWellness LLC, saying, “I believe in you.” This incredible act of kindness felt like a divine sign to Nicole—one that gave her the courage to keep pursuing her vision.

 


 

Pineal Gland Awareness and Fluoride’s Role

As Nicole delved deeper into holistic health, she learned about the pineal gland—a small, pea-shaped gland in the brain that produces melatonin and regulates sleep cycles. An imbalance in melatonin can disrupt sleep, lead to weight gain, and contribute to conditions like type 2 diabetes.

A 2020 study, Autism Spectrum Disorder (ASD): Disturbance of the Melatonin System and Its Implications, revealed that 67–89% of children with ASD experience sleep disturbances, such as shorter sleep duration, difficulty falling asleep, frequent night awakenings, and daytime sleepiness.

Nicole also discovered  during her research that suggested fluoride could calcify the pineal gland, hindering its ability to regulate melatonin production. With this knowledge, Nicole became passionate about protecting her autistic daughter from fluoride exposure. She also introduced detox baths with pink Himalayan Epsom salt and noticed improvements in her daughter’s sleep cycle, cognitive development, and overall physical health.

 


 

A Mission Rooted in Wellness

Nicole’s personal experiences fueled her passion for creating a toothpaste that strengthens teeth naturally—without fluoride. But her mission didn’t stop there. TrnscndWellness is committed to being a health and wellness company that serves consumers inclusively, offering products designed with empathy and care for diverse needs.

TrnscndWellness officially launched on November 19, 2024, and its flagship product, Talk toothpaste, is a testament to Nicole’s vision: an innovative, fluoride-free toothpaste that supports oral health while addressing unique sensitivities.



Credit:

Wu, Z., Huang, S., Zou, J., Wang, Q., Naveed, M., Bao, H., Wang, W., Fukunaga, K., & Han, F. (2020). Autism spectrum disorder (ASD): Disturbance of the melatonin system and its implications. Biomedicine & Pharmacotherapy, 130, 110496.  https://www.sciencedirect.com/science/article/pii/S0753332220306892

 

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1 comment


  • Tony K. Jan 27, 2025

    What an amazing story from an amazing founder. Purpose-built businesses represent the power of a dream, hard work, and determination intersecting at the right time.


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The Birth: Our Story & Our Why
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M
Talk Fluoride Free Natural Whitening w/ Hydroxyapatite Toothpaste
Monique Caradine- Kitchens
Talk came to GA and I love it!

I noticed that the fresh taste last longer than when I would use Colgate and I don't have to use as much to a clean feel! I would highly recommend this and exicited to discuss Talk on my podcast!

N
Talk Fluoride Free Natural Whitening w/ Hydroxyapatite Toothpaste
Nikki Pham
Better than Sensodyne

I typically use Sensodyne because I have sensitive teeth and bleeding gums. I've noticed since using Talk for the last two days my gums stopped bleeding! I really like this toothpaste!

B
Talk Fluoride Free Natural Whitening w/ Hydroxyapatite Toothpaste
Bader
Mouth feels great

It has been amazing. I feel my teeth being clean and bright white. I love the way my mouth feels afterwards. I’ve always seen ads with the charcoal color toothpaste and being able to try it now feels great. I will continue using the toothpaste as I look forward to healthier and stronger teeth!

W
Talk Fluoride Free Natural Whitening w/ Hydroxyapatite Toothpaste
Wendell
Light & soothing during use

I enjoyed using the Talk toothpaste. It has a powerful minty smell yet it’s light & soothing during use. It also adds another layer of interest knowing that all the ingredients are clean and intended to cleanse and remineralize my teeth. 10/10 highly recommended!

C
Talk Fluoride Free Natural Whitening w/ Hydroxyapatite Toothpaste
Cuba
Teeth whiter in a week

I love the taste and the mint flavor! Also love that it’s all natural, you digggggggg.

B
Talk Fluoride Free Natural Whitening w/ Hydroxyapatite Toothpaste
Bernard
Great product

I tried the toothpaste over the weekend and I liked it. I saw a change in my enamel color as well as it has a smooth taste. The color of it threw me off a little bit, but after reading the ingredients I see that it has charcoal in it. Overall it was a great product and I look forward to using it again.

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